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The exceptions come down to what irritates the injection site
Swift R & Davidson D, NIAAA, 1998
One trial used 2000 g/day vitamin B 12 and demonstrated a mean difference of 680 pg/mL (95% confidence interval 392.7 to 967.3) in favor of oral vitamin B 12
Note recent vomiting, diarrhea, illness, vigorous exercise, or major dietary changes because these may affect interpretation
If fever, chills, or other unexpected systemic reactions occur during an injection, it is likely due to the drug being delivered or possible contamination, rather than the bacteriostatic water itself
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