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Presented for research literature review only Harper S et al
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235 Procyanidins support gutliver axis function by upregulating tight junction proteins (e.g., zonula occludens-1, claudin-1), limiting endotoxin translocation, and protecting the liver from endotoxemia and inflammation
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To illustrate this spectrum of applications, Figure 2 highlights representative research directionsfrom developmental biology and disease modeling to drug screening, immune response studies, bioartificial kidney systems, and patient-specific therapeutic strategiesunderscoring the multifaceted role of kidney organoids in advancing kidney disease research and clinical translation
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