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Oxidized phosphatidylcholines in membrane-level cellular signaling: from biophysics to physiology and molecular pathology

Novo Nordisk did not do a great job projecting how much appetite there was for these drugs, says Levy

This is fundamentally different from how minoxidil works, which primarily dilates blood vessels, or how finasteride works, which blocks DHT production

Even though lower doses are presumably safer, using them would still require a new pre-IND safety justification, dose-range toxicology studies, and possibly a new manufacturing lot release. That would add ~12 years of delay