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Koren, N
We have shown that effective pharmacologic inhibition of GPX4 in PTC cells with direct inhibitor RSL3 induces a robust activation of ferroptosis, increased DNA damage, impaired DNA damage repair response due to reduced p-NPM1 levels, decreased cell viability and cell migration, as well as suppressed spheroid formation and viability in vitro
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CJC-1295 acts through the GHRH pathway to stimulate GH release with an extended half-life, while Ipamorelin works through ghrelin receptor activation, providing complementary mechanisms
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